Smart pH/temperature Sensitive Hydrogels with Tailored Transition Temperature
نویسندگان
چکیده
منابع مشابه
Frontal polymerization synthesis of temperature-sensitive hydrogels.
The study of hydrogels and their response to external environment is of special interest because of their potential as drug delivery systems,1,2 actuators,3 and separation devices.4,5 Temperature-sensitive hydrogels undergo a reversible swellingdeswelling transition with a small change of temperature near the phase transition point.6 A frequently studied thermosensitive hydrogel is based on sol...
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today hydrogels are considered as the materials that are able to play important role in drug delivery systems. to design an effective hydrogel applicable network, mathematical modeling has a critical role. a successful drug delivery device relies not only on intelligent network design but also on accurate prior mathematical modeling of drug release profiles. in this study, the modeling of the i...
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This paper uses the thermodynamic data of aqueous solutions of uncrosslinked poly(N-isopropylacrylamide) (PNIPAM) to study the phase transition of PNIPAM hydrogels. At a low temperature, uncrosslinked PNIPAM can be dissolved in water and form a homogenous liquid solution. When the temperature is increased, the solution separates into two liquid phases with different concentrations of the polyme...
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In the past few years, an increasing number of in situ-forming systems have been reported in the literature for various biomedical applications, including drug delivery, cell encapsulation, and tissue repair. There are several possible mechanisms that lead to in situ gel formation: solvent exchange, UV-irradiation, ionic cross-linkage, pH change, and temperature modulation. The thermosensitive ...
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This paper describes two types of polymeric micropumps based on the temperature-sensitive hydrogel poly(N-isopropylacrylamide). The gel actuators are realised as photopolymerised patterns and microgels. They are electrothermically controlled by resistive heating elements. The diffusion-based micropump contains a photopatterned monolithic actuator, which is placed within the pump chamber, and pr...
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ژورنال
عنوان ژورنال: Journal of the Mexican Chemical Society
سال: 2017
ISSN: 2594-0317,1870-249X
DOI: 10.29356/jmcs.v57i2.223